姓 名：卿志和
職 稱：教授
導師資格：博士生導師
郵 箱：qingzhihe@hnu.edu.cn
電 話：0731-85258649
研究方向：生物傳感與健康分析
簡介：卿志和，教授，博士生導師，國家優秀青年科學基金獲得者，“細胞化學”湖南省重點實驗室常務副主任，“健康化學”湖南省普通高等學校科技創新團隊帶頭人，長沙理工大學“湖湘學者”拔尖人才、科技處副處長、化學化工學院教授委員會主任、化學生物學專業負責人，入選全球前2%頂尖科學家榜單。從事生物傳感與健康分析研究工作，已主持國家自然科學基金優青項目、面上項目，湖南省自然科學基金重點項目、優青項目、企業技術服務項目等課題10余項，在 PNAS、Angew Chem、Anal Chem、等國內外高水平期刊上發表SCI收錄論文80余篇，授權專利10余件。獲得湖南省自然科學一等獎、湖南省自然科學二等獎、湖南省青年科技獎、湖南省教育系統優秀共產黨員、湖南省優秀研究生導師等獎勵或榮譽。擔任Chinese Chemical Letters、The Innovation、Journal of Analysis and Testing、《分析試驗室》等國內外期刊的編委或青年編委。
代表性論文：
[1] Quan Ke; Li Xiaoyuan; Deng Jiaqi; Chen Weiju; Zou Zhen; Chen Kun; Wu Linlin; Liu Juewen;Qing Zhihe*. Pt-Decorated Gold Nanoflares for High-Fidelity Phototheranostics: Reducing Side-Effects and Enhancing Cytotoxicity toward Target Cells, Angew. Chem. Int. Ed. 2024, 63, e202402881.
[2] Yanli Lei, Chuangchuang Li, Xinyue Ji, Haiyan Sun, Xiaowen Liu, Zenghui Mao, Weiju Chen, Zhihe Qing,* and Juewen Liu. Lowering Entropic Barriers in Triplex DNA Switches Facilitating Biomedical Applications at Physiological pH. Angew. Chem. Int. Ed. 2024, 63 , e202402123.
[3] Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang,* Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing,* Ronghua Yang*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed. 2022, 61, e202114504.
[4] Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, and Juewen Liu. Zn2+-Coordination-Driven RNAAssembly with Retained Integrity and Biological Functions. Angew. Chem. Int. Ed. 2021, 60, 22970–22976.
[5] Lifang Chen, Shuohui Xing, Yanli Lei, Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections. Angew. Chem. Int. Ed. 2021, 60, 23534–23539.
[6] Zhihe Qing, Guoyan Luo, Shuohui Xing, Zhen Zou, Yanli Lei, Juewen Liu*, Ronghua Yang*. Pt-S Bond Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage. Angew. Chem. Int. Ed.2020, 59, 14044 –14048.
[7] Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability. Chem. Sci. 2020, 11, 1985–1990.
[8] Zhihe Qing*, Jingyuan Xu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, Ronghua Yang*. In Situ Amplification-Based Imaging of RNA in Living Cells. Angew. Chem. Int. Ed. 2019, 58, 11574–11585.
